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Xentry-Gap19 inhibits Connexin43 hemichannel opening especially during hypoxic injury
Hypoxic injury results in cell death, tissue damage and activation of inflammatory pathways. This is mediated by pathological Connexin43 (Cx43) hemichannel (HC) opening resulting in osmotic and ionic imbalances as well as cytokine production perpetuating the inflammatory environment. Gap19 is an int...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223318/ https://www.ncbi.nlm.nih.gov/pubmed/32318976 http://dx.doi.org/10.1007/s13346-020-00763-y |