Melanocortin 4 receptor (MC4R) gene variants in children and adolescents having familial early-onset obesity: genetic and clinical characteristics

Melanocortin 4 receptor gene plays an important role in food intake, energy balance, and weight control. The autosomal dominantly inherited MC4R variants cause obesity by causing hyperphagia and decreased sense of satiety. Homozygous variants are rarely reported, and they cause earlier/severe obesit...

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Detalles Bibliográficos
Autores principales: Aykut, Ayça, Özen, Samim, Gökşen, Damla, Ata, Aysun, Onay, Hüseyin, Atik, Tahir, Darcan, Şükran, Özkinay, Ferda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223532/
https://www.ncbi.nlm.nih.gov/pubmed/32185475
http://dx.doi.org/10.1007/s00431-020-03630-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223532/
https://www.ncbi.nlm.nih.gov/pubmed/32185475
http://dx.doi.org/10.1007/s00431-020-03630-7

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