SAMD4 family members suppress human hepatitis B virus by directly binding to the Smaug recognition region of viral RNA

HBV infection initiates hepatitis B and promotes liver cirrhosis and hepatocellular carcinoma. IFN-α is commonly used in hepatitis B therapy, but how it inhibits HBV is not fully understood. We screened 285 human interferon-stimulated genes (ISGs) for anti-HBV activity using a cell-based assay, whic...

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Detalles Bibliográficos
Autores principales: Wang, Yuze, Fan, Xinrui, Song, Yunlong, Liu, Yifei, Liu, Ruixin, Wu, Jianfeng, Li, Xiaoling, Yuan, Quan, Fu, Guo, Xia, Ningshao, Han, Jiahuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223975/
https://www.ncbi.nlm.nih.gov/pubmed/32341522
http://dx.doi.org/10.1038/s41423-020-0431-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223975/
https://www.ncbi.nlm.nih.gov/pubmed/32341522
http://dx.doi.org/10.1038/s41423-020-0431-x

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