Cargando…

SAMD4 family members suppress human hepatitis B virus by directly binding to the Smaug recognition region of viral RNA

HBV infection initiates hepatitis B and promotes liver cirrhosis and hepatocellular carcinoma. IFN-α is commonly used in hepatitis B therapy, but how it inhibits HBV is not fully understood. We screened 285 human interferon-stimulated genes (ISGs) for anti-HBV activity using a cell-based assay, whic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yuze, Fan, Xinrui, Song, Yunlong, Liu, Yifei, Liu, Ruixin, Wu, Jianfeng, Li, Xiaoling, Yuan, Quan, Fu, Guo, Xia, Ningshao, Han, Jiahuai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223975/ https://www.ncbi.nlm.nih.gov/pubmed/32341522 http://dx.doi.org/10.1038/s41423-020-0431-x

Ejemplares similares

Smaug/SAMD4A Restores Translational Activity of CUGBP1 and Suppresses CUG-Induced Myopathy
por: de Haro, Maria, et al.
Publicado: (2013)

Smaug destroys a huge treasure
por: Götze, Michael, et al.
Publicado: (2014)

Smaug variants in neural and non-neuronal cells
por: Fernández-Alvarez, Ana Julia, et al.
Publicado: (2016)

Structural basis for binding of Drosophila Smaug to the GPCR Smoothened and to the germline inducer Oskar
por: Kubíková, Jana, et al.
Publicado: (2023)

Evolution and divergence of the mammalian SAMD9/SAMD9L gene family
por: Lemos de Matos, Ana, et al.
Publicado: (2013)

Global regulation of mRNA translation and stability in the early Drosophila embryo by the Smaug RNA-binding protein
por: Chen, Linan, et al.
Publicado: (2014)

The Smaug RNA-Binding Protein Is Essential for microRNA Synthesis During the Drosophila Maternal-to-Zygotic Transition
por: Luo, Hua, et al.
Publicado: (2016)

ATP is dispensable for both miRNA- and Smaug-mediated deadenylation reactions
por: Niinuma, Sho, et al.
Publicado: (2017)

SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies
por: Davidsson, Josef, et al.
Publicado: (2018)

Smaug1 mRNA-silencing foci respond to NMDA and modulate synapse formation
por: Baez, María Verónica, et al.
Publicado: (2011)

Non-invasive monitoring of glucocorticoid metabolite concentrations in urine and faeces of the Sungazer (Smaug giganteus)
por: Scheun, Juan, et al.
Publicado: (2018)

RNA binding protein SAMD4: current knowledge and future perspectives
por: Wang, Xin-Ya, et al.
Publicado: (2023)

Outcomes of Hematopoietic Cell Transplantation in Patients with Germline SAMD9/SAMD9L Mutations
por: Ahmed, Ibrahim A., et al.
Publicado: (2019)

RNA binding proteins Smaug and Cup induce CCR4–NOT-dependent deadenylation of the nanos mRNA in a reconstituted system
por: Pekovic, Filip, et al.
Publicado: (2023)

Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L
por: Peng, Shuxia, et al.
Publicado: (2022)

The F-box protein Bard (CG14317) targets the Smaug RNA-binding protein for destruction during the Drosophila maternal-to-zygotic transition
por: Cao, Wen Xi, et al.
Publicado: (2021)

NLRC4 inflammasome–dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice
por: Zhang, Peipei, et al.
Publicado: (2021)

Investigation of SAMD1 ablation in mice
por: Campbell, Bruce, et al.
Publicado: (2023)

miR-451 suppresses the malignant characteristics of colorectal cancer via targeting SAMD4B
por: Wu, Chunrong, et al.
Publicado: (2021)

SAMD1 attenuates antiphospholipid syndrome‐induced pregnancy complications
por: An, Ran, et al.
Publicado: (2023)

Functional Study of SAMD9L in Familial Gastric Cancer
por: Kaixuan, Xu, et al.
Publicado: (2023)

Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes
por: Sahoo, Sushree S., et al.
Publicado: (2020)

Ataxia-pancytopenia syndrome with SAMD9L mutations
por: Gorcenco, Sorina, et al.
Publicado: (2017)

CircSamd4: A novel biomarker for predicting vascular calcification
por: Zhou, Yuting, et al.
Publicado: (2021)

Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells
por: Thomas, Melvin E., et al.
Publicado: (2021)

SAMD1 attenuates antiphospholipid syndrome‐induced vascular injury and pregnancy complications
por: An, Ran, et al.
Publicado: (2022)

Emerging phenotypes linked to variants in SAMD9 and MIRAGE syndrome
por: Suntharalingham, Jenifer P., et al.
Publicado: (2022)

RNA-binding protein SAMD4 regulates skeleton development through translational inhibition of Mig6 expression
por: Niu, Ningning, et al.
Publicado: (2017)

RNA‐binding protein SAMD4A inhibits breast tumor angiogenesis by modulating the balance of angiogenesis program
por: Zhou, Meicen, et al.
Publicado: (2021)

Smaug regulates germ plasm synthesis and primordial germ cell number in Drosophila embryos by repressing the oskar and bruno 1 mRNAs
por: Siddiqui, Najeeb U., et al.
Publicado: (2023)

LncRNA SAMD12-AS1 Suppresses Proliferation and Migration of Hepatocellular Carcinoma via p53 Signaling Pathway
por: Wang, Juan, et al.
Publicado: (2022)

Germline SAMD9 Mutation in Siblings with Monosomy 7 and Myelodysplastic Syndrome
por: Schwartz, Jason R., et al.
Publicado: (2017)

A familial SAMD9 variant present in pediatric myelodysplastic syndrome
por: Rahim, Mahvish Q., et al.
Publicado: (2023)

SAMD13 serves as a useful prognostic biomarker for hepatocellular carcinoma
por: Yoo, Wonbeak, et al.
Publicado: (2023)

Non-replicating Vaccinia Virus TianTan Strain (NTV) Translation Arrest of Viral Late Protein Synthesis Associated With Anti-viral Host Factor SAMD9
por: Zhao, Ying, et al.
Publicado: (2020)

Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans
por: Buonocore, Federica, et al.
Publicado: (2017)

Germline SAMD9L truncation variants trigger global translational repression
por: Allenspach, Eric J., et al.
Publicado: (2021)

Functional requirements for a Samd14-capping protein complex in stress erythropoiesis
por: Ray, Suhita, et al.
Publicado: (2022)

Inflammation fuels bone marrow exhaustion caused by Samd9l mutation
por: Jung, Moonjung
Publicado: (2022)

SaMDE: A Self Adaptive Choice of DNDE and SPIDE Algorithms with MRLDE
por: Kumar, Pravesh, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f8vilmdcfdo5eu3673buvmef01