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Immunomodulatory Effect of Doxycycline Ameliorates Systemic and Pulmonary Inflammation in a Murine Polymicrobial Sepsis Model

Acute lung injury is an inflammatory condition developed after severe sepsis in response to excessive secretion of pro-inflammatory cytokines. Doxycycline is widely reported to possess immunomodulatory activity through inhibition of various inflammatory pathways. Considering the broad spectrum of an...

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Detalles Bibliográficos
Autores principales: Patel, Anasuya, Khande, Hemant, Periasamy, Hariharan, Mokale, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224120/
https://www.ncbi.nlm.nih.gov/pubmed/31955291
http://dx.doi.org/10.1007/s10753-020-01188-y