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Synthesis of diindolylmethane (DIM) bearing thiadiazole derivatives as a potent urease inhibitor
The current study describes synthesis of diindolylmethane (DIM) derivatives based-thiadiazole as a new class of urease inhibitors. Diindolylmethane is natural product alkaloid reported to use in medicinal chemistry extensively. Diindolylmethane-based-thiadiazole analogs (1–18) were synthesized and c...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224224/ https://www.ncbi.nlm.nih.gov/pubmed/32409737 http://dx.doi.org/10.1038/s41598-020-64729-3 |