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MicroRNA-132 regulates salt-dependent steady-state renin levels in mice

The body’s salt and fluid balance is regulated by the renin-angiotensin-aldosterone system. Generation of prostaglandin-E2 (PGE2) in a cyclo-oxygenase-2 (COX-2)-dependent manner in the macula densa, the salt-sensing cells of the kidney, plays a dominant role in renin regulation. Here we show that mi...

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Detalles Bibliográficos
Autores principales: van Zonneveld, Anton Jan, Au, Yu Wah, Stam, Wendy, van Gelderen, Sharon, Rotmans, Joris. I., Deen, Peter M. T., Rabelink, Ton J., Bijkerk, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224281/
https://www.ncbi.nlm.nih.gov/pubmed/32409785
http://dx.doi.org/10.1038/s42003-020-0967-4