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Protection of ZIKV infection-induced neuropathy by abrogation of acute antiviral response in human neural progenitors

It remains largely unknown how Zika virus (ZIKV) infection causes severe microcephaly in human newborns. We examined an Asian lineage ZIKV, SZ01, which similarly infected and demonstrated comparable growth arrest and apoptotic pathological changes in human neuroprogenitors (NPCs) from forebrain dors...

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Detalles Bibliográficos
Autores principales: Liu, Ling, Chen, Zhenyu, Zhang, Xin, Li, Shun, Hui, Yi, Feng, Hexi, Du, Yanhua, Jin, Guohua, Zhou, Xiaohui, Zhang, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224299/
https://www.ncbi.nlm.nih.gov/pubmed/30952992
http://dx.doi.org/10.1038/s41418-019-0324-7