HDAC1 inhibition ameliorates TDP-43-induced cell death in vitro and in vivo

TDP-43 pathology is a disease hallmark that characterizes both amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP). TDP-43 undergoes several posttranslational modifications that can change its biological activities and its aggregative propensity, which is a common ha...

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Detalles Bibliográficos
Autores principales: Sanna, Simona, Esposito, Sonia, Masala, Alessandra, Sini, Paola, Nieddu, Gabriele, Galioto, Manuela, Fais, Milena, Iaccarino, Ciro, Cestra, Gianluca, Crosio, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224392/
https://www.ncbi.nlm.nih.gov/pubmed/32409664
http://dx.doi.org/10.1038/s41419-020-2580-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224392/
https://www.ncbi.nlm.nih.gov/pubmed/32409664
http://dx.doi.org/10.1038/s41419-020-2580-3

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