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Mesoscale computational protocols for the design of highly cooperative bivalent macromolecules
The last decade has witnessed a swiftly increasing interest in the design and production of novel multivalent molecules as powerful alternatives for conventional antibodies in the fight against cancer and infectious diseases. However, while it is widely accepted that large-scale flexibility (10–100...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224399/ https://www.ncbi.nlm.nih.gov/pubmed/32409687 http://dx.doi.org/10.1038/s41598-020-64646-5 |