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Mesoscale computational protocols for the design of highly cooperative bivalent macromolecules

The last decade has witnessed a swiftly increasing interest in the design and production of novel multivalent molecules as powerful alternatives for conventional antibodies in the fight against cancer and infectious diseases. However, while it is widely accepted that large-scale flexibility (10–100...

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Detalles Bibliográficos
Autores principales: Saurabh, Suman, Piazza, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224399/
https://www.ncbi.nlm.nih.gov/pubmed/32409687
http://dx.doi.org/10.1038/s41598-020-64646-5