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When two are better than one: Modeling the mechanisms of antibody mixtures

It is difficult to predict how antibodies will behave when mixed together, even after each has been independently characterized. Here, we present a statistical mechanical model for the activity of antibody mixtures that accounts for whether pairs of antibodies bind to distinct or overlapping epitope...

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Detalles Bibliográficos
Autores principales: Einav, Tal, Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224563/
https://www.ncbi.nlm.nih.gov/pubmed/32365091
http://dx.doi.org/10.1371/journal.pcbi.1007830