SPOP promotes ubiquitination and degradation of MyD88 to suppress the innate immune response

As a canonical adaptor for the Toll-like receptor (TLR) family, myeloid differentiation primary response protein 88 (MyD88) has crucial roles in host defense against infection by microbial pathogens, and its dysregulation might induce autoimmune diseases. Here, we demonstrate that the chicken Cullin...

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Detalles Bibliográficos
Autores principales: Li, Qinghe, Wang, Fei, Wang, Qiao, Zhang, Na, Zheng, Jumei, Zheng, Maiqing, Liu, Ranran, Cui, Huanxian, Wen, Jie, Zhao, Guiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224567/
https://www.ncbi.nlm.nih.gov/pubmed/32365080
http://dx.doi.org/10.1371/journal.ppat.1008188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224567/
https://www.ncbi.nlm.nih.gov/pubmed/32365080
http://dx.doi.org/10.1371/journal.ppat.1008188

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