Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner

Synchronous neurotransmitter release is triggered by Ca(2+) binding to the synaptic vesicle protein Synaptotagmin 1, while asynchronous fusion and short-term facilitation is hypothesized to be mediated by plasma membrane-localized Synaptotagmin 7 (SYT7). We generated mutations in Drosophila Syt7 to...

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Detalles Bibliográficos
Autores principales: Guan, Zhuo, Quiñones-Frías, Monica C, Akbergenova, Yulia, Littleton, J Troy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224696/
https://www.ncbi.nlm.nih.gov/pubmed/32343229
http://dx.doi.org/10.7554/eLife.55443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224696/
https://www.ncbi.nlm.nih.gov/pubmed/32343229
http://dx.doi.org/10.7554/eLife.55443

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