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Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation
During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero level is low in neural stem cells and their immediate progeny, but is upregulated in larval neurons an...
Autores principales: | Samuels, Tamsin J., Arava, Yoav, Järvelin, Aino I., Robertson, Francesca, Lee, Jeffrey Y., Yang, Lu, Yang, Ching-Po, Lee, Tzumin, Ish-Horowicz, David, Davis, Ilan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225087/ https://www.ncbi.nlm.nih.gov/pubmed/32205310 http://dx.doi.org/10.1242/bio.049684 |
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