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Next-generation sequencing to dynamically detect mechanisms of resistance to ALK inhibitors in ALK-positive NSCLC patients: a case report

Tyrosine kinase inhibitors (TKIs) of the anaplastic lymphoma kinase gene (ALK) have significantly improved the quality of life and survival of non-small cell lung cancer (NSCLC) patients whose tumors harbor an ALK translocation. However, most of these patients relapse within 2 to 3 years as the tumo...

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Detalles Bibliográficos
Autores principales: Sánchez-Herrero, Estela, Blanco Clemente, Mariola, Calvo, Virginia, Provencio, Mariano, Romero, Atocha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225153/
https://www.ncbi.nlm.nih.gov/pubmed/32420077
http://dx.doi.org/10.21037/tlcr.2020.02.07