Cargando…

Expression of large tumour suppressor (LATS) kinases modulates chemotherapy response in advanced non-small cell lung cancer

BACKGROUND: The Hippo signalling pathway plays an important role in regulating organ size and cell proliferation. Down-regulation of large tumour suppressor (LATS) protein homologs LATS1 or LATS2 has been found in lung cancer. LATS1 and LATS2 are the core components of the Hippo signalling pathway....

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Susan Yang, Kwok, Hoi-Hin, Yang, Pan-Chyr, Ip, Mary Sau-Man, Minna, John Dorrance, Lam, David Chi-Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225163/
https://www.ncbi.nlm.nih.gov/pubmed/32420069
http://dx.doi.org/10.21037/tlcr.2020.03.26