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Expression of large tumour suppressor (LATS) kinases modulates chemotherapy response in advanced non-small cell lung cancer
BACKGROUND: The Hippo signalling pathway plays an important role in regulating organ size and cell proliferation. Down-regulation of large tumour suppressor (LATS) protein homologs LATS1 or LATS2 has been found in lung cancer. LATS1 and LATS2 are the core components of the Hippo signalling pathway....
Autores principales: | Luo, Susan Yang, Kwok, Hoi-Hin, Yang, Pan-Chyr, Ip, Mary Sau-Man, Minna, John Dorrance, Lam, David Chi-Leung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225163/ https://www.ncbi.nlm.nih.gov/pubmed/32420069 http://dx.doi.org/10.21037/tlcr.2020.03.26 |
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