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Heterogeneity of neoantigen landscape between primary lesions and their matched metastases in lung cancer

BACKGROUND: Personalized cancer vaccines based on tumor-derived neoantigens have shown strong and long-lasting antitumor effect in patients with some solid tumors. However, whether neoantigens identified from primary lesions could represent their metastatic lesions, and consequently the effect of va...

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Detalles Bibliográficos
Autores principales: Jiang, Tao, Cheng, Ruirui, Pan, Yuanwei, Zhang, Henghui, He, Ying, Su, Chunxia, Ren, Shengxiang, Zhou, Caicun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225166/
https://www.ncbi.nlm.nih.gov/pubmed/32420064
http://dx.doi.org/10.21037/tlcr.2020.03.03