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Heterogeneity of neoantigen landscape between primary lesions and their matched metastases in lung cancer
BACKGROUND: Personalized cancer vaccines based on tumor-derived neoantigens have shown strong and long-lasting antitumor effect in patients with some solid tumors. However, whether neoantigens identified from primary lesions could represent their metastatic lesions, and consequently the effect of va...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225166/ https://www.ncbi.nlm.nih.gov/pubmed/32420064 http://dx.doi.org/10.21037/tlcr.2020.03.03 |