Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity

In addition to hepatocytes, the liver comprises a host of specialised non-parenchymal cells which are important to consider in the development of in vitro models which are both physiologically and toxicologically relevant. We have characterized a 3D co-culture system comprising primary human hepatoc...

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Detalles Bibliográficos
Autores principales: Bell, Catherine C., Chouhan, Bhavik, Andersson, Linda C., Andersson, Håkan, Dear, James W., Williams, Dominic P., Söderberg, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
In Vitro Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225187/
https://www.ncbi.nlm.nih.gov/pubmed/32112222
http://dx.doi.org/10.1007/s00204-020-02682-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225187/
https://www.ncbi.nlm.nih.gov/pubmed/32112222
http://dx.doi.org/10.1007/s00204-020-02682-w

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