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An Integrated Dialysis Pharmacometric (IDP) Model to Evaluate the Pharmacokinetics in Patients Undergoing Renal Replacement Therapy

PURPOSE: Clearance via renal replacement therapy (RRT) can significantly alter the pharmacokinetic profile of drugs. The aim of this study was (i) to improve the use of clinical trial data and (ii) to provide a model that allows quantification of all aspects of drug elimination via RRT including ads...

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Detalles Bibliográficos
Autores principales: Broeker, Astrid, Vossen, Matthias G., Thalhammer, Florian, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A., Wicha, Sebastian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225193/
https://www.ncbi.nlm.nih.gov/pubmed/32409892
http://dx.doi.org/10.1007/s11095-020-02832-w