Genome-wide expression profiling reveals increased stability and mitochondrial energy metabolism of the human liver cell line HepaRG-CAR

Human liver cell line HepaRG is a well-known source of human hepatocyte-like cells which, however, displays limited biotransformation and a tendency to transform after 20 passages. The new HepaRG-CAR cell line overexpressing constitutive androstane receptor (CAR, NR1I3), a regulator of detoxificatio...

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Detalles Bibliográficos
Autores principales: Adam, Aziza A. A., Jongejan, Aldo, Moerland, Perry D., van der Mark, Vincent A., Oude Elferink, Ronald P., Chamuleau, Robert A. F. M., Hoekstra, Ruurdtje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225227/
https://www.ncbi.nlm.nih.gov/pubmed/32130581
http://dx.doi.org/10.1007/s10616-020-00384-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225227/
https://www.ncbi.nlm.nih.gov/pubmed/32130581
http://dx.doi.org/10.1007/s10616-020-00384-w

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