Magnesium Salt, a Simple Strategy to Improve Methadone Analgesia in Chronic Pain: An Isobolographic Preclinical Study in Neuropathic Mice

Analgesic efficacy of methadone in cancer and chronic non-cancer pains is greater than that of other opioids, probably because of its unique pharmacokinetics properties and also because it targets glutamatergic receptors in addition to µ-opioid receptors. However, methadone has drawbacks which are c...

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Detalles Bibliográficos
Autores principales: González, Valeria, Pelissier, Teresa, Cazanga, Victoria, Hernández, Alejandro, Constandil, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225258/
https://www.ncbi.nlm.nih.gov/pubmed/32457607
http://dx.doi.org/10.3389/fphar.2020.00566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225258/
https://www.ncbi.nlm.nih.gov/pubmed/32457607
http://dx.doi.org/10.3389/fphar.2020.00566

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