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Human Brain Organoids to Decode Mechanisms of Microcephaly

Brain organoids are stem cell-based self-assembling 3D structures that recapitulate early events of human brain development. Recent improvements with patient-specific 3D brain organoids have begun to elucidate unprecedented details of the defective mechanisms that cause neurodevelopmental disorders...

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Detalles Bibliográficos
Autores principales: Gabriel, Elke, Ramani, Anand, Altinisik, Nazlican, Gopalakrishnan, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225330/
https://www.ncbi.nlm.nih.gov/pubmed/32457578
http://dx.doi.org/10.3389/fncel.2020.00115