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The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?

Thyrotropin releasing hormone (TRH: Glp-His-Pro-NH(2)) is a peptide mainly produced by brain neurons. In mammals, hypophysiotropic TRH neurons of the paraventricular nucleus of the hypothalamus integrate metabolic information and drive the secretion of thyrotropin from the anterior pituitary, and th...

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Detalles Bibliográficos
Autores principales: Charli, Jean-Louis, Rodríguez-Rodríguez, Adair, Hernández-Ortega, Karina, Cote-Vélez, Antonieta, Uribe, Rosa María, Jaimes-Hoy, Lorraine, Joseph-Bravo, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225337/
https://www.ncbi.nlm.nih.gov/pubmed/32457627
http://dx.doi.org/10.3389/fphar.2020.00640