Pangolins Lack IFIH1/MDA5, a Cytoplasmic RNA Sensor That Initiates Innate Immune Defense Upon Coronavirus Infection

Zoonotic infections are an imminent threat to human health. Pangolins were recently identified as carriers and intermediate hosts of coronaviruses. Previous research has shown that infection with coronaviruses activates an innate immune response upon sensing of viral RNA by interferon-induced with h...

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Detalles Bibliográficos
Autores principales: Fischer, Heinz, Tschachler, Erwin, Eckhart, Leopold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225364/
https://www.ncbi.nlm.nih.gov/pubmed/32574256
http://dx.doi.org/10.3389/fimmu.2020.00939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225364/
https://www.ncbi.nlm.nih.gov/pubmed/32574256
http://dx.doi.org/10.3389/fimmu.2020.00939

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