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Delta-1 Functionalized Hydrogel Promotes hESC-Cardiomyocyte Graft Proliferation and Maintains Heart Function Post-Injury

Current cell transplantation techniques are hindered by small graft size, requiring high cell doses to achieve therapeutic cardiac remuscularization. Enhancing the proliferation of transplanted human embryonic stem cell-derived cardiomyocytes (hESC-CMs) could address this, allowing an otherwise subt...

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Detalles Bibliográficos
Autores principales: Gerbin, Kaytlyn A., Mitzelfelt, Katie A., Guan, Xuan, Martinson, Amy M., Murry, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225377/
https://www.ncbi.nlm.nih.gov/pubmed/32426414
http://dx.doi.org/10.1016/j.omtm.2020.04.011