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Antimicrobial peptide CGA-N12 decreases the Candida tropicalis mitochondrial membrane potential via mitochondrial permeability transition pore

Amino acid sequence from 65th to 76th residue of the N-terminus of Chromogranin A (CGA-N12) is an antimicrobial peptide (AMP). Our previous studies showed that CGA-N12 reduces Candida tropicalis mitochondrial membrane potential. Here, we explored the mechanism that CGA-N12 collapsed the mitochondria...

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Detalles Bibliográficos
Autores principales: Li, Ruifang, Zhao, Jiarui, Huang, Liang, Yi, Yanjie, Li, Aihua, Li, Dandan, Tao, Mengke, Liu, Youhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225414/
https://www.ncbi.nlm.nih.gov/pubmed/32368781
http://dx.doi.org/10.1042/BSR20201007