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28-day repeated oral dose toxicity study of an aqueous extract of Gryllus bimaculatus in sprague-dawley rat

This study was performed to demonstrate a No Observed Adverse Effect Level (NOAEL) for an aqueous extract of Gryllus bimaculatus. According to other studies, using dried material or extract with ethanol or methanol determined a NOAEL dose of 1000 mg/kg or 5000 mg/kg in rats. Therefore, the Gryllus b...

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Detalles Bibliográficos
Autores principales: Yu, Su Hyun, Yu, Su-Yeol, Lee, Bo-Su, Kim, Hyun-Jin, Kim, Mi-Ran, Lee, Young-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225595/
https://www.ncbi.nlm.nih.gov/pubmed/32426238
http://dx.doi.org/10.1016/j.toxrep.2020.04.006