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A Novel lncRNA, AK130181, Contributes to HIV-1 Latency by Regulating Viral Promoter-Driven Gene Expression in Primary CD4(+) T Cells

The functions and mechanisms of long non-coding RNAs (lncRNAs) in latent HIV-1 infection are not yet fully understood and warrant further research. In this study, we identified the newly inhibitory lncRNA AK130181 (also named LOC105747689), which is highly expressed in CD4(+) T lymphocytes latently...

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Detalles Bibliográficos
Autores principales: Li, Haiyu, Chi, Xiangbo, Li, Rong, Ouyang, Jing, Chen, Yaokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225600/
https://www.ncbi.nlm.nih.gov/pubmed/32408053
http://dx.doi.org/10.1016/j.omtn.2020.04.011