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A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion

OBJECTIVES: Glucose-stimulated insulin secretion is a critical function in the regulation of glucose homeostasis, and its deregulation is associated with the development of type 2 diabetes. Here, we performed a genetic screen using islets isolated from the BXD panel of advanced recombinant inbred (R...

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Detalles Bibliográficos
Autores principales: Berdous, Dassine, Berney, Xavier, Sanchez-Archidona, Ana Rodriguez, Jan, Maxime, Roujeau, Clara, Lopez-Mejia, Isabel C., Mynatt, Randall, Thorens, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225740/
https://www.ncbi.nlm.nih.gov/pubmed/32298772
http://dx.doi.org/10.1016/j.molmet.2020.100993