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A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion
OBJECTIVES: Glucose-stimulated insulin secretion is a critical function in the regulation of glucose homeostasis, and its deregulation is associated with the development of type 2 diabetes. Here, we performed a genetic screen using islets isolated from the BXD panel of advanced recombinant inbred (R...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225740/ https://www.ncbi.nlm.nih.gov/pubmed/32298772 http://dx.doi.org/10.1016/j.molmet.2020.100993 |