Endocytosis, trafficking and exocytosis of intact full-length botulinum neurotoxin type a in cultured rat neurons

Botulinum toxin A (BoNT/A) is a potent neurotoxin that acts primarily by silencing synaptic transmission by blocking neurotransmitter release. BoNT/A comprises a light chain (LC/A) intracellular protease and a heavy chain (HC/A) composed of a receptor binding domain (HC(C)/A) and a translocation dom...

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Detalles Bibliográficos
Autores principales: Solabre Valois, Luis, Wilkinson, Kevin A., Nakamura, Yasuko, Henley, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225749/
https://www.ncbi.nlm.nih.gov/pubmed/32088326
http://dx.doi.org/10.1016/j.neuro.2020.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225749/
https://www.ncbi.nlm.nih.gov/pubmed/32088326
http://dx.doi.org/10.1016/j.neuro.2020.02.009

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