Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells

Whereas hundreds of cells in the mouse embryonic aorta transdifferentiate to hematopoietic cells, only very few establish hematopoietic stem cell (HSC) identity at a single time point. The Gata2 transcription factor is essential for HSC generation and function. In contrast to surface-marker-based ce...

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Detalles Bibliográficos
Autores principales: Vink, Chris Sebastiaan, Calero-Nieto, Fernando Jose, Wang, Xiaonan, Maglitto, Antonio, Mariani, Samanta Antonella, Jawaid, Wajid, Göttgens, Berthold, Dzierzak, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225750/
https://www.ncbi.nlm.nih.gov/pubmed/32402290
http://dx.doi.org/10.1016/j.celrep.2020.107627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225750/
https://www.ncbi.nlm.nih.gov/pubmed/32402290
http://dx.doi.org/10.1016/j.celrep.2020.107627

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