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Plasmapheresis in Sepsis-induced Thrombotic Microangiopathy: A Case Series

INTRODUCTION: Cytokines and granulocyte elastase produced in sepsis cleave a disintegrin and metalloprotease with thrombospondin type I motif 13 (ADAMTS13) and deplete its levels. By this mechanism, sepsis results in microangiopathic hemolytic anemia (MAHA) with thrombocytopenia. Hence, the hypothes...

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Detalles Bibliográficos
Autores principales: Upadhya, Sushmita RS, Mahabala, Chakrapani, Kamat, Jayesh G, Jeganathan, Jayakumar, Kumar, Sushanth, Prabhu, Mayur V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225771/
https://www.ncbi.nlm.nih.gov/pubmed/32435099
http://dx.doi.org/10.5005/jp-journals-10071-23374