Attenuation of the Hypoxia Inducible Factor Pathway after Oncolytic Adenovirus Infection Coincides with Decreased Vessel Perfusion

The interplay between oncolytic virus infection and tumour hypoxia is particularly unexplored in vivo, although hypoxia is present in virtually all solid carcinomas. In this study, oncolytic adenovirus infection foci were found within pimonidazole-reactive, oxygen-poor areas in a colorectal xenograf...

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Detalles Bibliográficos
Autores principales: Yousaf, Iris, Kaeppler, Jakob, Frost, Sally, Seymour, Len W., Jacobus, Egon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225929/
https://www.ncbi.nlm.nih.gov/pubmed/32244697
http://dx.doi.org/10.3390/cancers12040851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225929/
https://www.ncbi.nlm.nih.gov/pubmed/32244697
http://dx.doi.org/10.3390/cancers12040851

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