P1′ Residue-Oriented Virtual Screening for Potent and Selective Phosphinic (Dehydro) Dipeptide Inhibitors of Metallo-Aminopeptidases

Designing side chain substituents complementary to enzyme binding pockets is of great importance in the construction of potent and selective phosphinic dipeptide inhibitors of metallo-aminopeptidases. Proper structure selection makes inhibitor construction more economic, as the development process t...

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Detalles Bibliográficos
Autores principales: Talma, Michał, Mucha, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225938/
https://www.ncbi.nlm.nih.gov/pubmed/32344658
http://dx.doi.org/10.3390/biom10040659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225938/
https://www.ncbi.nlm.nih.gov/pubmed/32344658
http://dx.doi.org/10.3390/biom10040659

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