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Safety and Activity of the Combination of Ceritinib and Dasatinib in Osteosarcoma

Osteosarcoma (OS) is the second most common cause of cancer-related death in pediatric patients. The insulin-like growth factor (IGF) pathway plays a relevant role in the biology of OS but no IGF targeted therapies have been successful as monotherapy so far. Here, we tested the effect of three IGF s...

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Detalles Bibliográficos
Autores principales: Beck, Olaf, Paret, Claudia, Russo, Alexandra, Burhenne, Jürgen, Fresnais, Margaux, Steimel, Kevin, Seidmann, Larissa, Wagner, Daniel-Christoph, Vewinger, Nadine, Lehmann, Nadine, Sprang, Maximilian, Backes, Nora, Roth, Lea, Neu, Marie Astrid, Wingerter, Arthur, Henninger, Nicole, El Malki, Khalifa, Otto, Henrike, Alt, Francesca, Desuki, Alexander, Kindler, Thomas, Faber, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225940/
https://www.ncbi.nlm.nih.gov/pubmed/32224911
http://dx.doi.org/10.3390/cancers12040793