Correlation of PKM2 and CD44 Protein Expression with Poor Prognosis in Platinum-Treated Epithelial Ovarian Cancer: A Retrospective Study

CD44, a surface marker for cancer stem cells, interacts with PKM2, a key regulator of aerobic glycolysis, and enhances the glycolytic phenotype of cancer cells leading to antioxidant protection and macromolecules’ synthesis. To clarify the clinical importance of this “cross-talk” as a mechanism of d...

Descripción completa

Detalles Bibliográficos
Autores principales: Papadaki, Chara, Manolakou, Stavroula, Lagoudaki, Eleni, Pontikakis, Spyros, Ierodiakonou, Despo, Vogiatzoglou, Konstantinos, Messaritakis, Ippokratis, Trypaki, Maria, Giannikaki, Linda, Sfakianaki, Maria, Kalykaki, Antonia, Mavroudis, Dimitrios, Tzardi, Maria, Souglakos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225941/
https://www.ncbi.nlm.nih.gov/pubmed/32326107
http://dx.doi.org/10.3390/cancers12041013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225941/
https://www.ncbi.nlm.nih.gov/pubmed/32326107
http://dx.doi.org/10.3390/cancers12041013

Ejemplares similares