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Correlation of PKM2 and CD44 Protein Expression with Poor Prognosis in Platinum-Treated Epithelial Ovarian Cancer: A Retrospective Study

CD44, a surface marker for cancer stem cells, interacts with PKM2, a key regulator of aerobic glycolysis, and enhances the glycolytic phenotype of cancer cells leading to antioxidant protection and macromolecules’ synthesis. To clarify the clinical importance of this “cross-talk” as a mechanism of d...

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Detalles Bibliográficos
Autores principales:	Papadaki, Chara, Manolakou, Stavroula, Lagoudaki, Eleni, Pontikakis, Spyros, Ierodiakonou, Despo, Vogiatzoglou, Konstantinos, Messaritakis, Ippokratis, Trypaki, Maria, Giannikaki, Linda, Sfakianaki, Maria, Kalykaki, Antonia, Mavroudis, Dimitrios, Tzardi, Maria, Souglakos, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225941/ https://www.ncbi.nlm.nih.gov/pubmed/32326107 http://dx.doi.org/10.3390/cancers12041013

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