Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy

Immune checkpoint blockade (ICB) monotherapy shows early promise for the treatment of nasopharyngeal carcinoma (NPC) in patients. Nevertheless, limited representative NPC models hamper preclinical studies to evaluate the efficacy of novel ICB and combination regimens. In the present study, we engraf...

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Detalles Bibliográficos
Autores principales: Liu, Wai Nam, Fong, Shin Yie, Tan, Wilson Wei Sheng, Tan, Sue Yee, Liu, Min, Cheng, Jia Ying, Lim, Sherlly, Suteja, Lisda, Huang, Edwin Kunxiang, Chan, Jerry Kok Yen, Iyer, Narayanan Gopalakrishna, Yeong, Joe Poh Sheng, Lim, Darren Wan-Teck, Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225949/
https://www.ncbi.nlm.nih.gov/pubmed/32331230
http://dx.doi.org/10.3390/cancers12041025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225949/
https://www.ncbi.nlm.nih.gov/pubmed/32331230
http://dx.doi.org/10.3390/cancers12041025

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