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Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy
Immune checkpoint blockade (ICB) monotherapy shows early promise for the treatment of nasopharyngeal carcinoma (NPC) in patients. Nevertheless, limited representative NPC models hamper preclinical studies to evaluate the efficacy of novel ICB and combination regimens. In the present study, we engraf...
Autores principales: | Liu, Wai Nam, Fong, Shin Yie, Tan, Wilson Wei Sheng, Tan, Sue Yee, Liu, Min, Cheng, Jia Ying, Lim, Sherlly, Suteja, Lisda, Huang, Edwin Kunxiang, Chan, Jerry Kok Yen, Iyer, Narayanan Gopalakrishna, Yeong, Joe Poh Sheng, Lim, Darren Wan-Teck, Chen, Qingfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225949/ https://www.ncbi.nlm.nih.gov/pubmed/32331230 http://dx.doi.org/10.3390/cancers12041025 |
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