STAT5 is Expressed in CD34(+)/CD38(−) Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms

Janus kinase 2 (JAK2) and signal transducer and activator of transcription-5 (STAT5) play a key role in the pathogenesis of myeloproliferative neoplasms (MPN). In most patients, JAK2 V617F or CALR mutations are found and lead to activation of various downstream signaling cascades and molecules, incl...

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Detalles Bibliográficos
Autores principales: Hadzijusufovic, Emir, Keller, Alexandra, Berger, Daniela, Greiner, Georg, Wingelhofer, Bettina, Witzeneder, Nadine, Ivanov, Daniel, Pecnard, Emmanuel, Nivarthi, Harini, Schur, Florian K. M., Filik, Yüksel, Kornauth, Christoph, Neubauer, Heidi A., Müllauer, Leonhard, Tin, Gary, Park, Jisung, de Araujo, Elvin D., Gunning, Patrick T., Hoermann, Gregor, Gouilleux, Fabrice, Kralovics, Robert, Moriggl, Richard, Valent, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225958/
https://www.ncbi.nlm.nih.gov/pubmed/32326377
http://dx.doi.org/10.3390/cancers12041021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225958/
https://www.ncbi.nlm.nih.gov/pubmed/32326377
http://dx.doi.org/10.3390/cancers12041021

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