Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors

Activins belong to the transforming growth factor (TGF)-β family of multifunctional cytokines and signal via the activin receptors ALK4 or ALK7 to activate the SMAD2/3 pathway. In some cases, activins also signal via the bone morphogenetic protein (BMP) receptor ALK2, causing activation of the SMAD1...

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Detalles Bibliográficos
Autores principales: Olsen, Oddrun Elise, Hella, Hanne, Elsaadi, Samah, Jacobi, Carsten, Martinez-Hackert, Erik, Holien, Toril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225989/
https://www.ncbi.nlm.nih.gov/pubmed/32235336
http://dx.doi.org/10.3390/biom10040519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225989/
https://www.ncbi.nlm.nih.gov/pubmed/32235336
http://dx.doi.org/10.3390/biom10040519

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