Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells

Myeloid cell leukemia 1 (Mcl-1) and B-cell lymphoma 2 (Bcl-2) proteins are promising targets for cancer therapy. Here, we investigated the structure–activity relationships (SARs) and performed molecular docking analysis of renieramycin T (RT) and its analogues and identified the critical functional...

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Detalles Bibliográficos
Autores principales: Petsri, Korrakod, Yokoya, Masashi, Tungsukruthai, Sucharat, Rungrotmongkol, Thanyada, Nutho, Bodee, Vinayanuwattikun, Chanida, Saito, Naoki, Takehiro, Matsubara, Sato, Ryo, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226000/
https://www.ncbi.nlm.nih.gov/pubmed/32260280
http://dx.doi.org/10.3390/cancers12040875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226000/
https://www.ncbi.nlm.nih.gov/pubmed/32260280
http://dx.doi.org/10.3390/cancers12040875

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