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E-Cadherin in Pancreatic Ductal Adenocarcinoma: A Multifaceted Actor during EMT

Epithelial-to-mesenchymal transition (EMT) is a step-wise process observed in normal and tumor cells leading to a switch from epithelial to mesenchymal phenotype. In tumors, EMT provides cancer cells with a metastatic phenotype characterized by E-cadherin down-regulation, cytoskeleton reorganization...

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Detalles Bibliográficos
Autores principales: Sommariva, Michele, Gagliano, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226001/
https://www.ncbi.nlm.nih.gov/pubmed/32331358
http://dx.doi.org/10.3390/cells9041040