The Cytosolic Phospholipase A(2)α N-Terminal C2 Domain Binds and Oligomerizes on Membranes with Positive Curvature

Group IV phospholipase A(2)α (cPLA(2)α) regulates the production of prostaglandins and leukotrienes via the formation of arachidonic acid from membrane phospholipids. The targeting and membrane binding of cPLA(2)α to the Golgi involves the N-terminal C2 domain, whereas the catalytic domain produces...

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Detalles Bibliográficos
Autores principales: Ward, Katherine E., Sengupta, Ranjan, Ropa, James P., Amiar, Souad, Stahelin, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226022/
https://www.ncbi.nlm.nih.gov/pubmed/32331436
http://dx.doi.org/10.3390/biom10040647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226022/
https://www.ncbi.nlm.nih.gov/pubmed/32331436
http://dx.doi.org/10.3390/biom10040647

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