SOX2 Expression and Transcriptional Activity Identifies a Subpopulation of Cancer Stem Cells in Sarcoma with Prognostic Implications

Stemness in sarcomas is coordinated by the expression of pluripotency factors, like SOX2, in cancer stem cells (CSC). The role of SOX2 in tumor initiation and progression has been well characterized in osteosarcoma. However, the pro-tumorigenic features of SOX2 have been scarcely investigated in oth...

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Detalles Bibliográficos
Autores principales: Menendez, Sofia T., Rey, Veronica, Martinez-Cruzado, Lucia, Gonzalez, M. Victoria, Morales-Molina, Alvaro, Santos, Laura, Blanco, Verónica, Alvarez, Carlos, Estupiñan, Oscar, Allonca, Eva, Rodrigo, Juan Pablo, García-Castro, Javier, Garcia-Pedrero, Juana Maria, Rodriguez, Rene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226033/
https://www.ncbi.nlm.nih.gov/pubmed/32295077
http://dx.doi.org/10.3390/cancers12040964

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226033/
https://www.ncbi.nlm.nih.gov/pubmed/32295077
http://dx.doi.org/10.3390/cancers12040964

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