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Genetic Deficiency of the Histamine H(4)-Receptor Reduces Experimental Colorectal Carcinogenesis in Mice

Colorectal cancer (CRC), a severe complication of inflammatory bowel diseases, is a common type of cancer and accounts for high mortality. CRC can be modeled in mice by application of the tumor promoter, azoxymethane (AOM), in combination with dextran sodium sulfate (DSS), which are able to induce c...

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Detalles Bibliográficos
Autores principales: Schirmer, Bastian, Rother, Tamina, Bruesch, Inga, Bleich, Andre, Werlein, Christopher, Jonigk, Danny, Seifert, Roland, Neumann, Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226035/
https://www.ncbi.nlm.nih.gov/pubmed/32276475
http://dx.doi.org/10.3390/cancers12040912