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Genetic Deficiency of the Histamine H(4)-Receptor Reduces Experimental Colorectal Carcinogenesis in Mice
Colorectal cancer (CRC), a severe complication of inflammatory bowel diseases, is a common type of cancer and accounts for high mortality. CRC can be modeled in mice by application of the tumor promoter, azoxymethane (AOM), in combination with dextran sodium sulfate (DSS), which are able to induce c...
Autores principales: | Schirmer, Bastian, Rother, Tamina, Bruesch, Inga, Bleich, Andre, Werlein, Christopher, Jonigk, Danny, Seifert, Roland, Neumann, Detlef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226035/ https://www.ncbi.nlm.nih.gov/pubmed/32276475 http://dx.doi.org/10.3390/cancers12040912 |
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